P939 - THE RISK OF CARDIOMETABOLIC DISEASES IN YOUNG ADULTS WITH DISABILITIES: A NATIONWIDE COHORT STUDY

P939

THE RISK OF CARDIOMETABOLIC DISEASES IN YOUNG ADULTS WITH DISABILITIES: A NATIONWIDE COHORT STUDY

E. Joo^1,*, D. W. Shin¹, I. Y. Cho¹, K. D. Han²

¹Department of Family Medicine/Supportive Care Center, Samsung Medical Center, ²Department of Statistics and Actuarial Science, Soongsil University, Seoul, Korea, Republic Of

Rationale:  Although the incidence of cardiometabolic diseases such as diabetes mellitus(DM) and hypertension is increasing among young adults, evidence regarding these conditions in those with disabilities remains limited. We aimed to investigate the risk of DM, hypertension and dyslipidemia in young adults with disabilities. 

Methods: We conducted a retrospective cohort study using data from the National Disability Registration System linked to the Korean National Health Insurance Service database. A total of 5,329,659 individuals aged 19–39 years who underwent health screening between 2009 and 2012 were followed until 2022. Young adults with disabilities were categorized by the severity (none, mild, or severe) and type of disability. Cox proportional hazards models were used to estimate adjusted hazard ratios (aHRs) with 95% confidence intervals (CIs), adjusting for age, sex, income, smoking, alcohol, physical activity, and obesity.

Results: Among the study population, 72,234 individuals had disabilities. After multivariable adjustment, disability was associated with increased risks of DM (aHR 1.36, 95% CI: 1.32–1.40), hypertension (aHR 1.28, 95% CI: 1.26–1.30), and dyslipidemia (aHR 1.21, 95% CI: 1.19–1.23). Stratified analyses showed elevated risks across both mild and severe disabilities for DM (mild, aHR 1.24, 95% CI 1.19–1.29; severe, aHR 1.67, 95% CI 1.58–1.76), hypertension (mild, aHR 1.22, 95% CI 1.20–1.25; severe, aHR 1.43, 95% CI 1.38–1.47), and dyslipidemia (mild, aHR 1.19, 95% CI 1.17–1.21; severe, aHR 1.26, 95% CI 1.23–1.30).

Conclusion: Young adults with disabilities demonstrated increased risks of DM, hypertension, and dyslipidemia. These associations were especially prominent in individuals with severe disabilities and specific disability types. Early identification and targeted health strategies are essential to reduce the burden of cardiometabolic diseases in this population. 

Disclosure of Interest: None declared