P775 - ADVANCED MATERNAL AGE AND FETAL DEVELOPMENT: THE ROLE OF DIETARY FIBRE

P775

ADVANCED MATERNAL AGE AND FETAL DEVELOPMENT: THE ROLE OF DIETARY FIBRE

M. Puche-Juárez^1,2,3,*, J. M. Toledano^1,2,3, J. Moreno-Fernandez^1,2,3,4, J. Diaz-Castro^1,2,3,4, L. Manzanares-Rios¹, C. De Paco-Matallana⁵, M. P. Carrillo⁶, E. Martín-Alvarez⁶, J. J. Ochoa^1,2,3,4

¹Department of Physiology, University of Granada, ²Centro de Investigación biomédica (CIBM), ³Institute of Nutrition and Food Technology ''José Mataix Verdú'', ⁴Instituto de Investigación Biosanitaria (IBS), Granada, ⁵Obstetrics and Gynaecology, Universitary Hospital ''Virgen de la Arrixaca'', Murcia, ⁶Obstetrics and Gynaecology, Universitary Hospital ''Virgen de las Nieves'', Granada, Spain

Rationale: Delayed childbearing is a growing trend in developed countries, associated with factors such as access to higher education, employment and economic stability. This demographic change has led to the definition of advanced maternal age (AMA) as nulliparous women 35≥ years old. Nutrition during pregnancy is key to maternal health and its programming effect in the offspring and nutritional needs and the ability of the body to absorb nutrients vary over time. Those changes could affect fetal development and therefore, the health of the newborn.

Methods: A total of 200 mothers were recruited in the second trimester of gestation in two hospitals in Spain. They were divided in: control group, <35 years old; AMA group, ≥35 years old. An online Food Frequency Questionnaire (FFQ) was used to obtain the amount of nutrients consumed on average in grams per day; anthropometric measures form the newborn were collected on a database. Comparisons between groups and correlation analyses were carried out using RStudio software.

Results: Fibre intake was significantly lower in the AMA group compared to the control group (p<0.05). A significant negative correlation was found between total fibre intake and newborn head circumference (HC) with a correlation coefficient (r) of -0.41 and p = 0.03.

Conclusion: A lower fibre intake in the AMA group compared to the control group, despite no differences in the cereal food group, may be explained by the lower variability and quality in the choice of cereals. The negative correlation found between fibre and HC can be explained by the reduction of glucose spikes that fibre consumption induces, which in turn leads to a decrease in insulin secretion. Therefore, the dietary habits of AMA women should be reviewed and their dietary recommendations should be personalised due to the possible influence of these on anthropometric measurements of newborns.

Disclosure of Interest: None declared