P875 - PROGNOSTIC IMPACT OF SARCOPENIC OBESITY ON HOSPITAL ADMISSION

P875

PROGNOSTIC IMPACT OF SARCOPENIC OBESITY ON HOSPITAL ADMISSION

M. Molina Ortega^1,*, L. Dalla Rovere^2,3, A. Guerrini⁴, R. Fernández-Jiménez^3,5, M. García Olivares^2,3, C. Hardy Añón², C. Herola², J. M. García-Almeida^2,3

¹Universidad Autónoma de Madrid, Madrid, ²Endocrinology and Nutrition Department , Hospital QuironSalud Málaga, ³Universidad de Málaga, Málaga, Spain, ⁴Department of Science and Technology for Humans and the Environment, Università Campus Bio-Medico di Roma, Rome, Italy, ⁵Endocrinology and Nutrition Department , Hospital Quirónsalud Málaga, Málaga, Spain

Rationale: Sarcopenic obesity (SO) is characterized by the coexistence of excess fat mass (FM) and sarcopenia. One of the scenarios where SO has been least studied is hospital admission. In this population obesity represents 31% of admissions. In these circumstances, there is a need to evaluate SO as a prognostic factor in accordance with the definition proposed by ESPEN-EASO. The main objective of this study was to evaluate whether SO is an independent prognostic factor for mortality at hospital admission.

Methods: A retrospective descriptive study was carried out in 156 patients with obesity admitted to Hospital QuirónSalud Málaga (2019-2023). Obesity was defined as a high percentage of Fat Mass (FM) in accordance with EASO/ESPEN guidelines. A complete nutritional assessment was performed in these patients (MUST, SGA and GLIM criteria). Complementary to this assessment, bioelectrical impedance was measured with a phase-sensitive impedance device (Nutrilab™, Akern, Florence, Italy). Also, handgrip strength was measured with a dynamometer (Jamar®). Data was analyzed based on the presence of obesity or sarcopenic obesity (SO) following the EASO/ESPEN criteria.

Results: Of the 156 patients with obesity (67.9% male, mean age 61.6 ± 15.1 years, mean BMI 31.140 ± 5.037 kg/m²), 32.1% of the patients met the EASO/ESPEN criteria for SO while 67.9% only had a high FM% measured by BIA according to EASO/ESPEN guidelines.

        - Survival was lower in the group of patients with SO 76% [65%-88.8%, 95% CI] vs 88% [82%-94.2%, 95% CI]. 

        - The hazard ratio of the group of patients with obesity to the group of patients with sarcopenic obesity was 0.46 (0.22-0.99, p=0.047).

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Conclusion: Our study confirms a high prevalence of patients with SO within a cohort of patients with obesity (defined as a high %FM).32.1% of our sample met SO criteria. Patients with obesity had 54% less risk of death than patients with SO demonstrating how SO is a prognostic factor at hospital admission.

Disclosure of Interest: None declared