PD608 - INFLUENCE OF SEX AND AGE ON A BODY SHAPE INDEX, CLINICAL, AND LABORATORY PROFILES IN THE BRAZILIAN ADULT POPULATION

PD608

INFLUENCE OF SEX AND AGE ON A BODY SHAPE INDEX, CLINICAL, AND LABORATORY PROFILES IN THE BRAZILIAN ADULT POPULATION

T. P. Minari^1,*, J. F. Vilela-martin ², J. R. R. Uyemura², L. N. Cosenso-Martin ², J. C. Yugar-toledo², L. P. Pisani¹

¹Bioscience, Federal University of São Paulo, Santos, ²Internal Medicine, State Faculty of Medicine of São José do Rio Preto, São José do Rio Preto, Brazil

Rationale: Sex and age differences influence clinical and laboratory profiles, contributing to distinct cardiometabolic risk patterns. Traditional anthropometric measures, such as Body Mass Index (BMI), have limitations in estimating visceral adiposity. A Body Shape Index (ABSI), derived from waist circumference, height, and weight, was developed to overcome these limitations by better capturing abdominal fat distribution.

Methods: Data were obtained from the Brazilian National Health Survey, a nationally representative sample of adults. A total of 400 individuals were included, ensuring adequate power to detect moderate effects. Comparisons between men and women were performed using t-tests or Mann–Whitney tests. Age categories were analyzed using ANOVA or Kruskal–Wallis tests. Logistic and linear regression models with sex–age interaction terms were applied to assess independent associations.

Results: Men showed higher systolic blood pressure (132 vs. 125 mmHg, p<0.01) and triglyceride levels (165 vs. 140 mg/dL, p<0.05), whereas women presented higher HDL-cholesterol (54 vs. 46 mg/dL, p<0.01). Older adults (>60 years) had a higher prevalence of elevated fasting glucose (32% vs. 18% in younger adults, p<0.01). ABSI values were higher in men than women (0.082 vs. 0.078, p<0.01) and in older compared with younger adults (0.083 vs. 0.079, p<0.01). ABSI remained independently associated with elevated blood pressure and fasting glucose after adjustment for BMI. Age-related effects on ABSI were stronger in men.

Conclusion: Sex and age differences in clinical and laboratory profiles were evident in Brazilian adults. ABSI improved cardiometabolic risk stratification beyond BMI, supporting its use in epidemiological research and clinical practice to identify vulnerable groups and inform public health strategies.

Disclosure of Interest: None declared