PD488
COMPARISON OF THE ENERGY EXPENDITURE MEASURED BY CALORIMETRY WITH THE ESTIMATE BY HARRIS-BENEDICT EQUATION AND THE ANSA/OMS SUGGESTED ENERGY REQUIREMENTS AMONG ADULT PATIENTS WITH HIV/AIDS.
E. Perez-Cruz1,*, A. ALTAMIRANO-JIMENEZ1, K. I. GOMEZ-ALANIZ1, M. A. JUAN-GOMEZ1
1Metabolic Unit and Nutritional Support, Hospital Juárez de México , Mexico, Mexico
Rationale: We aim was to compare the energy expenditure (EE) estimate by Harris-Benedict equation (HBe), the Association of Nutrition Services Agencies and the World Health Organization (ANSA/WHO) suggested energy requirements with the EE measured by indirect calorimetry (IC).
Methods: Pilot study in patients of both sexes, aged > 18 years, recruited from a High-Specialty Referral Hospital. The EE was measured using a CCM Express isothermal titration calorimeter (MGC Diagnostics) and the EE was estimated using the HBe and the ANSA/WHO suggested energy requirements.
The percentages of accurate, underestimated, and overestimated predictions of estimated EE were determined using the HBe and the ANSA/WHO for all subjects. Estimated precision was defined as the percentage of subjects whose estimated EE was within ± 10% of the measured EE.
Results: Thirty subjects were included, with a mean age of 40.7 ± 10.2 years. The majority of participants were male, 86.7%. The mean BMI was 22.8 ± 3.9 kg/m2, 50% of the patients had an SGA C.
The EE, measured by calorimetry, was 1595.0 ± 343.19 kcal/day. The EE was estimated using the HBe and the ANSA/WHO, which were 1495.33 ± 178.44 kcal/day and 2403.05 ± 559.45 kcal/day (p < 0.001), respectively Table 1. The EE estimated using the HBe has a precision of 40%, underestimated EE measured by calorimetry by 40% and overestimated by 20% (p = 0.135). Meanwhile, EE estimated using ANSA/WHO energy requirements has a precision of 6.7%, underestimated EE measured by IC by 10% and overestimated by 83.3%. (p < 0.01).
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Conclusion: The EE estimated using the HBe showed a difference of -6.2% in comparison to calorimetry; while ANSA/WHO showed a difference of 50.6%. Calculating EE using the HBe is often a useful tool in units where a calorimeter is not available.
Disclosure of Interest: None declared