P337 - ASSOCIATIONS BETWEEN NUTRITIONAL ASSESSMENT PARAMETERS AND SURVIVAL IN CANCER PATIENTS RECEIVING ORAL NUTRITIONAL SUPPORT

P337

ASSOCIATIONS BETWEEN NUTRITIONAL ASSESSMENT PARAMETERS AND SURVIVAL IN CANCER PATIENTS RECEIVING ORAL NUTRITIONAL SUPPORT

J. J. Raposo López^1,*, M. López Ruano¹, T. Armenta Joya¹, B. Molina Baena¹, M. Tapia Sanchiz¹, E. Carrillo López¹, C. Sager La Ganga¹, S. González Castañar¹, S. Amar¹, L. González Vallejo¹, G. Martínez Trascasa¹, M. Sampedro-Núñez¹ on behalf of Juan José Raposo López, Marta López Ruano and Teresa Armenta Joya contributed equally to this work.

¹Endocrinología y Nutrición, Hospital Universitario La Princesa, Madrid, Spain

Rationale: The relevance of nutritional status in cancer patients is known; however, evidence on whether clinical and nutritional assessment tools can predict survival when oral nutritional support is initiated is limited. This study aims to evaluate whether parameters like GLIM criteria, handgrip strength, BIA, muscular ultrasound, and blood biomarkers are associated with mortality in cancer patients receiving nutritional care.

Methods: A prospective observational study was conducted on 25 cancer patients (mean age 67±9 years) assessed by the Nutrition Unit within 30 days of oncology referral. Baseline evaluation included cancer type, metastasis status (40%), oncologic treatment (84% chemotherapy, 10% immunotherapy, 10% radiotherapy), GLIM criteria, handgrip strenght, BIA, and blood tests. Oral nutritional support was initiated (45% high-calorie, high-protein formulas; 33% diabetes-specific; 17% peptide-based; remaining renal-specific formulas). Follow-up was completed in 20 cases with blood tests, BIA, ultrasound, and handgrip strength.

Results: Median survival was 1,254 days. GLIM criteria showed an association with survival: patients with a score of 0 had 100% survival, while those with scores 1 and 2 had 44% and 46%, respectively. Sarcopenia was less prevalent in survivors (14%) compared to those who died (50%). Correlation analysis revealed significant associations between handgrip strenght, muscle mass and albumin. Survival analysis indicated higher potassium levels while creatinine and prealbumin decreased in deceased patients over time. Total body fat percentage was higher in survivors. Ultrasound data did not predict survival.

Conclusion: GLIM and sarcopenia criteria may help predict survival in cancer patients receiving oral nutritional support. BIA parameters, albumin, and dynamometry may offer additional prognostic value. Larger studies are needed to confirm these findings.

Disclosure of Interest: None declared