PD916 - MEDITERRANEAN DIET ADHERENCE AND DYSLIPIDEMIA IN YOUTH WITH TYPE 1 DIABETES: EVIDENCE FROM A MEDIATION ANALYSIS

PD916

MEDITERRANEAN DIET ADHERENCE AND DYSLIPIDEMIA IN YOUTH WITH TYPE 1 DIABETES: EVIDENCE FROM A MEDIATION ANALYSIS

N. Arslan^1,*, F. AYYILDIZ², D. GÜNEŞ KAYA³

¹Department of Nutrition and Dietetics, Sağlık Bilimleri Üniversitesi Gülhane Faculty of Health Sciences , ²Department of Nutrition and Dietetics, Gazi University, Faculty of Health Sciences, Ankara, ³Pediatrics, İstanbul University Cerrahpasa Faculty of Medicine, Istanbul, Türkiye

Rationale: Mediterranean diet adherence has been associated with improved metabolic outcomes, yet its relationship with dyslipidemia in youth with type 1 diabetes (T1D) remains unclear.The aim of this study is to evaluate the factors explaining the relationship between adherence to the Mediterranean diet and dyslipidemia in children with type 1 diabetes.

Methods: This cross-sectional study included 10-18 years with T1D. Mediterranean diet adherence was assessed using the KIDMED index. Dyslipidemia status and HbA1c levels were obtained from clinical records. Mediation analysis was performed using bootstrap methods, adjusting for age and sex.

Results: Lower dyslipidemia risk was significantly associated with lower HbA1c levels (B = −0.9219, p <0.001). In turn, higher KIDMED scores were associated with lower HbA1c scores (B = −0.9824, p < 0.001). The direct effect of KIDMED score on dyslipidemia risk was not statistically significant (B = 0.1525, p = 0.593). However, a significant indirect effect via HbA1c was observed (B = 0.9056, 95% CI: 0.5013–1.3735), indicating mediation.

Conclusion: Mediterranean diet adherence may reduce dyslipidemia risk in youth with T1D indirectly through improved glycemic control. These findings highlight HbA1c as a key mechanistic pathway linking diet quality to lipid outcomes in youth with T1D. 

Disclosure of Interest: None declared