PP206 - ESTIMATED MINERAL INTAKE AT INTENSIVE CARE UNIT ADMISSION AND ITS ASSOCIATION WITH LENGTH OF STAY

PP206

ESTIMATED MINERAL INTAKE AT INTENSIVE CARE UNIT ADMISSION AND ITS ASSOCIATION WITH LENGTH OF STAY

M. Galvis-Pedraza^1,*, T. van Zutphen¹, I. J. Riphagen², H. Buter³, L. F. Beumeler⁴, E. C. Boerma¹

¹Department of Sustainability & Wellbeing, Faculty Campus Fryslân, University of Groningen, ²Certe Medical Diagnostics & Advise, Certe Medical Diagnostics & Advise, ³Department of Intensive Care, Frisius Medical Center, ⁴Research Group Digital Innovation in Healthcare and Social Work, NHL Stenden University of Applied Sciences, Leeuwarden, Netherlands

Rationale: Micronutrient disturbances are common in the intensive care unit (ICU) population, but the relationship between estimated mineral intake at ICU admission and ICU length of stay (LOS) remains unclear. We aimed to assess whether estimated mineral intake is associated with ICU LOS independent of systemic inflammation.

Methods: We performed an exploratory analysis of 79 adults admitted to a mixed ICU in the Netherlands. Estimated intake of sodium, potassium, calcium, magnesium, zinc, selenium and phosphorus was assessed by a dietitian interview, ideally within 24 hours of ICU admission, using patient or proxy report when needed. Descriptive statistics were applied. ICU LOS (hours) was analysed using reduced negative binomial regression adjusted for C-reactive protein (CRP); predictors were standardised per 1 SD.

Results: Median estimated daily intakes in mg were 1945 [1771 - 2162] for sodium, 3804 [3591 - 4012] for potassium, 1204 [1103 - 1298] for calcium, 1624 [1517 - 1729] for phosphorus, 11 [11 – 12] for zinc, 337 [318 -380] for magnesium, 46 [43 – 51] for selenium. In the adjusted model, higher sodium intake was associated with longer ICU LOS (rate ratio [RR] 1.44, 95% CI 1.16 – 1.81; p = 0.004), whereas higher zinc intake was associated with shorter ICU LOS (RR 0.68, 95% CI 0.48 – 0.98, p = 0.038). Associations for remaining minerals were not statistically significant. CRP was positively associated with ICU LOS (RR 1.98, 95% CI 1.61 – 2.46; p < 0.001).

Conclusion: Estimated mineral intake at ICU admission showed selective associations with ICU LOS after adjustment for systemic inflammation. In particular, higher sodium intake and lower zinc intake were associated with longer ICU stay. These findings should be interpreted cautiously, as intake estimates in acute illness may reflect underlying health status and early disease-related changes rather than causal effects.

Disclosure of Interest: None declared