PD879 - EVALUATION OF DISEASE-RELATED MALNUTRITION WITH MORPHOFUNCTIONAL ASSESSMENT IN CANCER PATIENTS: ANYVIDA GROUP.

PD879

EVALUATION OF DISEASE-RELATED MALNUTRITION WITH MORPHOFUNCTIONAL ASSESSMENT IN CANCER PATIENTS: ANYVIDA GROUP.

M. J. López ¹, E. Arjonilla¹, E. Sanchez¹, N. Y. Wu Xiong ², B. Alabadí-Pardiñes³, A. Jiménez ⁴, C. Mañas C⁴, J. Ruiz ¹, I. Gonzalo Montesinos⁵, R. Fernandez Jimenez^6,*, J. M. García Almeida⁶ on behalf of Anyvida Group

¹Department of Endocrinology and Nutrition, Hospital General Universitario Morales Meseguer, Murcia, ²Department of Endocrinology and Nutrition, Hospital Clinico Universitario de Valencia,, ³Department of Endocrinology and Nutrition, INCLIVA Biomedical Research Institute, ⁴Department of Endocrinology and Nutrition, Hospital General Universitario de Valencia,, Valencia, ⁵Department of Endocrinology and Nutrition, Hospital Universitario de Fuenlabrada, Madrid, ⁶Department of Endocrinology and Nutrition, Hospital Virgen de la Victoria, Malaga, Spain

 

Rationale: Malnutrition is highly prevalent in cancer patients and is associated with poorer outcomes, making early detection essential. While the Global Leadership Initiative on Malnutrition (GLIM) criteria and the Subjective Global Assessment (SGA) enable diagnosis, morphofunctional tools may improve nutritional assessment.

Analyze the association between morphofunctional parameters and GLIM and SGA criteria according to malnutrition severity, as well as their complementary clinical value.

Methods: A cross-sectional study was conducted in 518 cancer patients. Nutritional status was assessed by GLIM and SGA, classifying patients as moderately or severely malnourished. Anthropometry, muscle function (handgrip strength), body composition, and functional tests were evaluated. Statistical analysis was performed using the Mann-Whitney U test.

 

Results: The study included 518 cancer patients (mean age 66.3±11.6 years; 57.8% men). Malnutrition was diagnosed in 98.0% by GLIM and 90.5% by SGA.

The most frequent tumors were esophagogastric (17%), followed by colon (11.9%) and pancreas (9%).

Significant differences in anthropometric, muscle strength, and bioimpedance parameters were observed between moderate and severe malnutrition using both GLIM and SGA criteria, with worse results in severe cases.

Similar findings were seen in muscle ultrasound area and Y-axis (at rest and contraction), with no differences in the X-axis.

Functional test differences were significant only with SGA; GLIM showed a trend toward worse outcomes, without statistical significanc

Conclusion: Severe malnutrition is associated with worse nutritional and functional status compared to moderate malnutrition, as most studied parameters—except functional tests—showing significant differences regardless of diagnostic method. SGA seems more sensitive than GLIM for detecting functional impairment.

Disclosure of Interest: None declared