P370 - LONG-TERM RESULTS USING NUTRITIONAL INDICATORS IN COLORECTAL CANCER SURGERY-CACHEXIA AND MODIFIED GLASGOW PROGNOSTIC SCORE（MGPS）-

P370

LONG-TERM RESULTS USING NUTRITIONAL INDICATORS IN COLORECTAL CANCER SURGERY

-CACHEXIA AND MODIFIED GLASGOW PROGNOSTIC SCORE（MGPS）-

S. Furuya^1,*, K. Shiraishi¹, K. Takahashi¹, K. Takiguchi¹, K. Matsuoka¹, Y. Higuchi¹, T. Ozawa¹, R. Saito¹, W. Izumo¹, S. Maruyama¹, K. Shoda¹, Y. Kawaguchi¹, H. Amemiya¹, D. Ichikawa¹

¹First Department of Surgery, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan

Rationale: Elderly patients with rectal cancer are at increased risk of postoperative complications and poor prognosis, with malnutrition being a major contributing factor. This study evaluated the association between preoperative nutritional status and postoperative outcomes in patients aged ≥75 years, compared with younger patients.

Methods: We retrospectively analyzed 155 rectal cancer patients who underwent curative surgery, dividing them into two groups: ≥75 years (n=48) and <75 years (n=107). Nutritional status was assessed using the Prognostic Nutritional Index (PNI), Geriatric Nutritional Risk Index (GRNI), and modified Glasgow Prognostic Score (mGPS). Postoperative complications and 5-year mortality were compared using appropriate statistical tests.

Results: Patients aged ≥75 years showed significantly poorer nutritional status compared to younger patients. The mean serum albumin level was significantly lower in the elderly group (3.75 g/dL) than in the younger group (4.10 g/dL, p=0.0002). Similarly, the elderly group had lower mean PNI (44.6 vs. 48.0, p=0.0015) and GRNI (97.3 vs. 104.4, p=0.0006), indicating a higher risk of malnutrition.mGPS ≥1 was more common in the elderly group (19% vs. 3%, p=0.018), and mGPS = 2 was seen only in the elderly (6.3% vs. 0%, p=0.048).Although anastomotic leakage rates were similar, ileus was more frequent in the elderly (16.7% vs. 5.6%).Five-year mortality was higher in the elderly group (16.7% vs. 7.5%, p=0.036), particularly in those with poor nutritional scores.

Conclusion: Elderly rectal cancer patients showed poorer preoperative nutritional status and worse outcomes. Nutritional assessment using PNI, GRNI, and mGPS may help identify high-risk individuals and guide perioperative interventions.

Disclosure of Interest: None declared