PD356 - A DISEASE-SPECIFIC APPROACH TO MALNUTRITION SCREENING IN CIRRHOSIS: VALIDITY AND RELIABILITY OF THE TURKISH LDUST AND ITS DIAGNOSTIC PERFORMANCE AGAINST NRS-2002

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PD356

A DISEASE-SPECIFIC APPROACH TO MALNUTRITION SCREENING IN CIRRHOSIS: VALIDITY AND RELIABILITY OF THE TURKISH LDUST AND ITS DIAGNOSTIC PERFORMANCE AGAINST NRS-2002

S. GÜNEŞ1,2,*, S. DEMİR FİLİZ2, B. ÖZGÜREL3, S. VATANSEVER4

1Department of Nutrition and Dietetics, Ataturk Training and Research Hospital, 2Nutrition and Dietetics Program, 3Department of Statistics, Izmir Tinaztepe University, 4Department of Gastroenterology, Ataturk Training and Research Hospital, Izmir, Türkiye

 

Rationale: Malnutrition is common in cirrhosis and linked to complications, prolonged hospitalization, and mortality. Assessment of nutrition and detection of malnutrition is challenging due to fluid retention and limited disease-specific tools. This study evaluated the validity and reliability of the Turkish Liver Disease Undernutrition Screening Tool (Tr-LDUST) and its criterion validity against NRS-2002

Methods: 161 cirrhotic patients were included. LDUST was cross-culturally adapted using forward–backward translation. Content validity was assessed with Content Validity Ratio (CVR) and Content Validity Index (CVI). Internal consistency was evaluated with Cronbach’s alpha and item–total correlations. Construct validity was examined using Exploratory Factor Analysis (EFA) and Confirmatory Factor Analysis (CFA).Convergent validity was assessed with Composite Reliability (CR) and Average Variance Extracted (AVE).Criterion validity was evaluated against NRS-2002 using Spearman correlation and ROC analysis.

Results: CVR and CVI exceeded thresholds.Tr-LDUST showed good internal consistency(α=0.816; item–total 0.520–0.711). EFA revealed two factors explaining 55.6% variance.CFA indicated acceptable fit (χ²/df=2.112; GFI=0.964; CFI=0.972; RMSEA=0.083).CR 0.713-0.822 and AVE 0.608–0.454 supported convergent validity. Strong correlation with NRS-2002(r=0.704, p<0.001).ROC AUC=0.933; cut-off ≥10:sensitivity 95%,specificity 78.7%,NPV 99.1%

Conclusion: Tr-LDUST is a valid, reliable, and clinically applicable tool for malnutrition risk in cirrhosis.High sensitivity and negative predictive value enable early detection of malnutrition.It can be applied in routine practice, even by healthcare professionals without specialized nutrition training, and offers a disease-specific advantage in patients with fluid retention.

Disclosure of Interest: None declared