P742 - INFLUENCE OF ABDOMINAL OBESITY INDICATORS ON ALL-CAUSE MORTALITY IN INDIVIDUALS UNDERGOING HEMODIALYSIS: A COHORT STUDY IN BRAZIL

P742

INFLUENCE OF ABDOMINAL OBESITY INDICATORS ON ALL-CAUSE MORTALITY IN INDIVIDUALS UNDERGOING HEMODIALYSIS: A COHORT STUDY IN BRAZIL

C. A. Martins¹, L. P. Klippel², K. S. Barbosa³, L. B. Leandro³, E. H. Furtado⁴, E. S. Neto¹, L. B. Salaroli^1,*

¹Graduate Program in Collective Health, ²Graduate Program in Nutrition and Health, ³Integrated Health Education, Federal University of Espirito Santo, Vitória, ⁴Physiological Sciences, Federal University of Maranhão, São Luís , Brazil

Rationale: Abdominal obesity has been associated with a worse prognosis in individuals with chronic kidney disease undergoing hemodialysis, increasing the risk of all-cause mortality. This study aimed to evaluate the impact of different abdominal obesity indicators on the mortality of individuals on hemodialysis.

Methods: A retrospective cohort study used data from individuals undergoing regular hemodialysis in Espírito Santo, Brazil, collected in 2019 and followed until 2022. Sociodemographic, clinical, and anthropometric data were analyzed alongside mortality records from the Mortality Information System. Abdominal obesity indicators assessed included waist circumference, waist-to-height ratio, and conicity index. Survival was estimated using Kaplan-Meier curves and compared via the log-rank test. Cox regression models evaluated associations between these indicators and mortality, adjusting for age, sex, skin color, and body mass index.

Results: The sample included 375 individuals (mean age: 59.5 years, 159 women, 216 men). Abdominal obesity was highly prevalent: 77.3% had an increased waist-to-height ratio, 62.1% an elevated conicity index, and 60.7% an increased waist circumference. Kaplan-Meier analysis showed lower survival for those with a high conicity index. Cox regression indicated that an elevated conicity index was significantly associated with a 49.7% higher risk of all-cause mortality (p = 0.0466), whereas waist circumference and waist-to-height ratio showed no significant association.

Conclusion: Among the abdominal obesity indicators analyzed in hemodialysis patients, the conicity index proved to be the best predictor of mortality. Therefore, its use may be recommended for the early identification of high-risk individuals, enabling more targeted interventions to improve survival and quality of life in this population.

Disclosure of Interest: None declared