P1070 - RANDOMIZED CONTROLLED TRIAL OF PREOPERATIVE ORAL SEMI-SOLID HYDRATION SOLUTION IN BREAST SURGERY UNDER GENERAL ANESTHESIA.

P1070

RANDOMIZED CONTROLLED TRIAL OF PREOPERATIVE ORAL SEMI-SOLID HYDRATION SOLUTION IN BREAST SURGERY UNDER GENERAL ANESTHESIA.

S. Ito^1,*, I. Tabei¹, T. Okamoto¹, I. Utsumi², S. Omi²

¹Department of Surgery, ²Department of Anesthesiology, The Jikei University School of Medicine Daisan Hospital, Tokyo, Japan

Rationale: Although preoperative oral hydration using non-fiber fluids up to 2 hours before surgery has been confirmed as safe and effective, its usage is still not practical in Japan. This study aimed to evaluate the safety, patient compliance, and effects of a semi-solid hydration gel solution in patients undergoing breast surgery under general anesthesia.

Methods: In this prospective, randomized controlled trial, patients scheduled for elective breast surgery were allocated to either an oral rehydration group(GEL) or a conventional fasting group(NPO). The GEL group consumed 400 g of gel solution(OS-1 Jelly®) in the evening before surgery and 400g of gel solution on the morning of surgery (up to 2 hours preoperatively). At anesthesia induction, gastric contents were aspirated to measure volume and pH, and incidences of vomiting and aspiration were also recorded. Intraoperative hydration status was assessed using urine output, fractional excretion of sodium (FENa), urinary osmolarity, skin moisture measurements, and stroke volume variation (SVV).Patient-reported outcomes were assessed via a questionnaire.

Results: A total of 43 patients (21 in the NPO and 22 in the GEL) were analyzed. The gastric content volume(9.6 vs 10.4ml, respectively) and pH(2.14 vs 2.06), with no observed cases of vomiting or aspiration. Urinary osmolarity(433 vs 374mOsm/kg), and FENa(0.82 vs 0.79). Urine output(53 vs 66 ml), skin moisture measurements difference (-1.4 vs -0.2), SVV(12.1% vs 9.6%), indicating better fluid balance for GEL. From the questionnaire, thirst was reported less in the GEL group (56% vs 6%).

Conclusion: Despite safety and effect of preoperative oral rehydration has been confirmed, preoperative fasting is still practiced in Japan, this attempt to use gel solution may promote preoperative hydration method and be expected to be used as an alternative to preoperative drinking.

Disclosure of Interest: None declared