P835 - COGNITIVE IMPAIRMENT AND ITS RELATIONSHIP WITH MOBILITY, QUALITY OF LIFE, FUNCTIONALITY, AND GENIOHYOID MUSCLE PARAMETERS IN OLDER STROKE PATIENTS

P835

COGNITIVE IMPAIRMENT AND ITS RELATIONSHIP WITH MOBILITY, QUALITY OF LIFE, FUNCTIONALITY, AND GENIOHYOID MUSCLE PARAMETERS IN OLDER STROKE PATIENTS

N. M. Catikkas¹, V. Binay Safer^2,*, U. Safer³, A. Gultekin², I. Tasci⁴

¹Geriatric Medicine, Sancaktepe Sehit Prof. Dr. İlhan Varank Egitim ve Arastirma Hastanesi, ²Physical Medicine and Rehabilitation, ³Geriatric Medicine, ⁴Internal Medicine, Health Science University, Istanbul, Türkiye

Rationale: No study has concurrently assessed cognitive impairment-related functional measures and geniohyoid (GH) muscle parameters. This study aims to investigate the associations between cognitive impairment and mobility, quality of life, functionality, and ultrasonographic GH muscle parameters in older stroke patients.

Methods: Stroke patients admitted to a Physiotherapy and Rehabilitation Clinic were prospectively enrolled. Cognitive status was evaluated using the Mini-Mental State Examination (MMSE), while mobility, quality of life, and functionality were assessed using the Rivermead Mobility Index (RMI), Stroke-specific Quality of Life (SSQOL) scale, and Brunnstrom stages, respectively. Disability was measured via the Modified Rankin Scale (mRS). GH muscle parameters, including subcutaneous fat thickness, muscle thickness (MT), and cross-sectional area (CSA), were analyzed using ultrasonography. Multivariable analysis was conducted to examine the associations between cognitive impairment and functional as well as GH muscle parameters.

Results: The study included 41 patients (mean age: 69.9±7.4 years; 58.5% male), with 58.5% (n=24) presenting cognitive impairment (MMSE <24). Cognitive impairment was independently associated with lower RMI scores (p=0.007), decreased SSQOL (p=0.019), reduced Brunnstrom stages (p=0.038, 0.009, and 0.049), higher mRS scores (p=0.043), and lower GHMT and GHCSA values (p=0.032 and 0.011, respectively).

Conclusion: This study demonstrates significant associations between cognitive impairment and both functional and ultrasonographic GH muscle variables in older stroke patients. As the first investigation to evaluate these parameters collectively, it underscores the need for multicenter, longitudinal studies to further explore these relationships.

Disclosure of Interest: None declared