PP041
SARCOPENIA DEFINED BY DIFFERENT CRITERIA IS ASSOCIATED WITH POOR QUALITY OF LIFE IN THE DIABETIC OLDER ADULTS
A. B. Tombul1, K. N. Yılmaz2, S. Arı2, M. K. Kılıç2, A. Okyar Baş2,*
1Department of Internal Medicine, 2Department of Internal Medicine, Division of Geriatrics,, Ankara Training and Research Hospital, Ankara, Türkiye
Rationale: Diabetes mellitus (DM) and Sarcopenia are linked to loss of functional independence and decreased quality of life (QoL) in older adults. Although they frequently coexist, data on the relationship between QoL, sarcopenia, and comprehensive geriatric assessment (CGA) parameters in older adults with diabetes remain limited.
Methods: Patients over 65 years and with Type 2 DM were prospectively included. QoL was assessed using the OPQOL-Brief scale. Sarcopenia was defined as:1)Global Leadership Initiative on Sarcopenia (GLIS)[ a)Low muscle strength (MS):(handgrip strength (HGS) and 5-item chair stand test (5-CST)),b)Low muscle mass (MM):(skeletal muscle mass index (SMMI) adjusted for body mass index (BMI) which was evaluated by bioelectrical impedance analysis (BIA)),c)Low muscle-specific strength(HGS/arm circumference)] and 2) European Working Group on Sarcopenia in Older People (EWGSOP-2) (Low MS plus Low MM).
Results: A total of 69 diabetic older adults were included (median age 71 (IQR: 67–74) years; 60.9% female). Patients were categorized into 2 groups as poor QoL (n=33, 47.8%) and normal QoL (n=36, 52.2%).Regarding sarcopenia parameters, the poor QoL group demonstrated higher SARC-F scores, rates of all GLIS components (low strength, mass, and muscle-specific strength), and a frequency of confirmed sarcopenia via EWGSOP-2 (p<0.05). Correlation analysis confirmed that sarcopenia was significantly associated with lower QoL (p<0.05)
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Conclusion: To the best of our knowledge, it is the first study revealing the relationship between GLIS criteria and QoL in older adults with diabetes Our findings suggest that sarcopenia impacts not only physical health but also social parameters such as QoL, and integrating sarcopenia screening into the routine clinical management of older diabetic patients may help to preserve QoL.
Disclosure of Interest: None declared