P919 - TOLERANCE AND GLYCEMIC CONTROL OF A HIGH-PROTEIN, HIGH-CALORIE, REDUCED IN CARBOHYDRATE ENTERAL FORMULA IN HOSPITALIZED PATIENTS WITH DIABETE S

P919

TOLERANCE AND GLYCEMIC CONTROL OF A HIGH-PROTEIN, HIGH-CALORIE, REDUCED IN CARBOHYDRATE ENTERAL FORMULA IN HOSPITALIZED PATIENTS WITH DIABETE S

A. Vidal Casariego^1,*, S. J. Cadahía Lema¹, F. J. Pita Gutiérrez¹, G. J. Lugo Rodríguez¹, T. J. Martínez Ramonde¹

¹Unidad de Nutrición , Complejo Hospitalario Universitario de A Coruña, A Coruña, Spain

Rationale: Malnutrition and glycemic control are key concerns in hospitalized patients requiring enteral nutrition (EN), particularly those with diabetes. 

Methods: A prospective observational study was conducted in hospitalized patients with diabetes receiving a high-protein, high-calorie, reduced in carbohydrates enteral formula (Nutrison Advanced Diason Energy HP). Nutritional parameters, tolerance, and glycemic control were analyzed.

Results: Thirty-six patients were included, with a mean age of 69.6 years (14.3), 63.9% male, and mainly admitted to Internal Medicine (19.4%) and Oncology (11.1%). Type 2 diabetes was present in 86.1%, type 1 in 2.8%, and other types in 11.1%. The mean BMI was 24.7 kg/m² (6.3), and prealbumin increased from 19.0 mg/dL (7.24) to 20.1 mg/dL (7.40) (p = 0.307). The mean administered EN volume was 930 mL/day (138), achieving 96.7% of the target. Diarrhea occurred in 47.2%, with a mean duration of 1.56 days (2.63). The mean stool frequency was 1.04 per day (0.99), with no significant differences between laxative users and non-users (p > 0.05). The mean HbA1c was 6.71% (1.17), and the mean glucose level was 170 mg/dL (51.8), with 60.2% of glucose values remaining below 180 mg/dL. Glycemic variability, expressed as the coefficient of variation, was 24..2 (124). No significant differences were observed in glycemic parameters between corticosteroid users and non-users.

Conclusion: The enteral formula studied was well tolerated, with high adherence to prescribed volumes and manageable gastrointestinal effects, while achieving an adequate glycemic control in hospitalized patients with diabetes. These findings underscore the need for tailored nutritional strategies to optimize metabolic outcomes in this population.

Disclosure of Interest: None declared