P422 - COMPARISON OF CREATININE HEIGHT INDEX LEVEL CHANGES IN PREDICTING VENTILATOR WEANING OUTCOMES OF PATIENTS WITH PROLONGED MECHANICAL VENTILATION

P422

COMPARISON OF CREATININE HEIGHT INDEX LEVEL CHANGES IN PREDICTING VENTILATOR WEANING OUTCOMES OF PATIENTS WITH PROLONGED MECHANICAL VENTILATION

M. Kumala^1,*, N. R. M. Manikam¹, A. N. Auerkari²

¹Nutrition, ²Anesthesiology and Intensive Care, Faculty of Medicine University of Indonesia, Jakarta, Indonesia

Rationale: Monitoring muscle mass in intensive care is crucial, yet there is currently no practical method for accurately depicting body muscle mass. Creatinine Height Index (CHI) can serve as an indicator of body muscle mass. It is hypothesized that there are differences in the changes of Creatinine Height Index associated with successful weaning in patients undergoing prolonged ventilator use. 

Methods: This study is a prospective observational study conducted on Prolonged Mechanical Ventilation (PMV) patients at dr. Cipto Mangunkusumo General Hospital and University of Indonesia Hospital. Creatinine Height Index (CHI) measurements were taken within the first 72 hours of intubation and repeated upon extubation or at a maximum of day 14 of ventilator use. 

Results: There were 27 subjects with an average age of 46 years and a majority being male (67%). Initial and final CHI values did not differ significantly between those who successfully weaned and those who did not. However, the change in CHI values differed significantly statistically between those who successfully weaned and those who did not (p = 0.009). The group that failed to wean experienced a change in CHI values from -18,3% to 23,7%, with a mean of -3,9%. 

Conclusion: There was a statistically significant difference in the change in CHI values between the groups that successfully weaned and those that did not. The group that failed to wean showed a decrease in CHI values, while the group that successfully weaned did not experience this.

Disclosure of Interest: None declared