PT17. - EFFECTS OF A MULTIDISCIPLINARY TRANSITIONAL NUTRITIONAL INTERVENTION ON PHYSICAL ACTIVITY IN ACUTELY ADMITTED OLDER PATIENTS WITH MALNUTRITION OR RISK OF MALNUTRITION: A SECONDARY ANALYSIS OF A RANDOMIZED CONTROLLED TRIAL (OPTINAM)
PT17.
EFFECTS OF A MULTIDISCIPLINARY TRANSITIONAL NUTRITIONAL INTERVENTION ON PHYSICAL ACTIVITY IN ACUTELY ADMITTED OLDER PATIENTS WITH MALNUTRITION OR RISK OF MALNUTRITION: A SECONDARY ANALYSIS OF A RANDOMIZED CONTROLLED TRIAL (OPTINAM)
J. M. Mansfeldt1, A. L. L. Andersen2,3,*, T. Kallemose2,3, R. L. Nielsen2,3, M. B. Houlind2,4,5, H. G. Juul-Hansen2, A. M. Beck6, O. Bornæs2,3, F. Magkos1, O. Andersen2,3,7, M. M. Pedersen2,3
1Department of Nutrition, Exercise and Sports, University of Copenhagen, 2Department of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, 3Faculty of Health and Medical Sciences, University of Copenhagen, Department of Clinical Medicine, 4The Capital Region Pharmacy, 5Department of Drug Design and Pharmacology, University of Copenhagen, 6Dietetic and Nutritional Research Unit, Herlev-Gentofte University Hospital, 7Emergency Department, Copenhagen University Hospital Amager and Hvidovre, Copenhagen, Denmark
Rationale: Older patients acutely admitted to the hospital are characterized by malnutrition and physical inactivity. Consequently, we investigated the impact of a multidisciplinary transitional nutritional intervention on physical activity and functional performance after acute hospitalization.
Methods: This secondary prespecified analysis of the randomized controlled trial, OptiNAM, compares a multidisciplinary and transitional nutritional intervention with standard care in older (≥65 years) acutely admitted patients with malnutrition or at-risk of malnutrition. Outcomes were assessed at baseline, and 8- and 16 weeks post-discharge and included physical activity (step count and uptime) collected by triaxial accelerometer (activPAL3™), and functional performance (the De Morton Mobility Index score, handgrip strength, sit-to-stand ability, and walking speed). The Intention-To-Treat analysis was linear regression evaluating the between-group differences in change between discharge and 8- and 16 weeks, respectively. A sub-analysis evaluated the effect of meeting individual energy- or protein recommendations (≥75% vs. <75%).
Results: 105 acutely admitted older patients were randomized to an intervention (n=50) or a control (n=55) group. The ITT and the sub-analysis revealed no intervention effect on physical activity or functional performance outcomes 8- and 16 weeks post-discharge.
Conclusion: A multidisciplinary transitional nutritional intervention was not superior to standard care in improving physical activity and functional performance at 8- and 16 weeks post-discharge in acutely admitted older patients with malnutrition or at risk of malnutrition.
Disclosure of Interest: None declared