P772 - BRIDGING THE GAP IN HPN: A REAL-WORLD ANALYSIS OF INFUSION ADHERENCE

P772

BRIDGING THE GAP IN HPN: A REAL-WORLD ANALYSIS OF INFUSION ADHERENCE

E. Awawdeh², I. Papier¹, H. Bar Yoseph², I. Chermesh^2,2,*

¹nursing, ²Gastroenterology, Rambam health care campus, Haifa, Israel

Rationale: Home parenteral nutrition (HPN) is a critical therapy for patients with compromised gastrointestinal function. While HPN is prescribed daily or intermittently and adjusted based on clinical goals such as weight maintenance, clinicians often lack objective data on the actual volumes infused. This information gap may lead to misinterpretation of treatment effectiveness. Remedix Care, in collaboration with Eitan Medical’s validated remote-monitoring infusion pump, addresses this challenge by accurately recording infused volumes in real-time. The aim of this study was to evaluate discrepancies between prescribed and actual infused parenteral nutrition (PN) volumes in patients receiving HPN.

Methods: A retrospective analysis was conducted on all HPN patients monitored remotely at a single
outpatient clinic. All home treatment sessions within the four weeks preceding March 28, 2025, were included. We
analyzed adherence to both prescribed infusion volumes and frequency.

Results: Data from 454 treatment days involving 35 patients were analyzed. Patients were monitored for a mean of 13.76
± 8.92 days (median 13). The mean daily prescribed volume was 1395.52 ± 490.38 mL (median 1200 mL). Volume
adherence on days when infusions were actually administered was high (87.43 ± 26.54%, median 94.7%). However,
when adherence was assessed based on infusion schedule per week, the rate was significantly lower (63.15 ± 32.12%,
median 71.43%; p < 0.001). Notably, 20% of patients received <80% of their prescribed total weekly volume

Conclusion: Discrepancies between prescribed and delivered HPN volumes are common. While volume adherence is
high on infusion days, overall treatment adherence declines due to missed sessions. These findings suggest that
prescribing fewer infusion days per week may improve compliance. Remote monitoring systems that provide validated,
real-time data are essential to optimize HPN management and clinical outcomes.

Disclosure of Interest: None declared