P906 - ROLE OF SOCIOECONOMIC FACTORS ON THE DEVELOPMENT OF SARCOPENIC OBESITY:EVIDENCE FROM THE ENGLISH LONGITUDINAL STUDY OF AGEING

P906

ROLE OF SOCIOECONOMIC FACTORS ON THE DEVELOPMENT OF SARCOPENIC OBESITY:

EVIDENCE FROM THE ENGLISH LONGITUDINAL STUDY OF AGEING

S. Nishioka^1,2,*, B. I. Avan³

¹London School of Hygiene and Tropical Medicine, London, United Kingdom, ²Department of Nutrition Science, Faculty of Nursing and Nutrition, University of Nagasaki, Nagayo-cho, Japan, ³Department of Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom

Rationale: Sarcopenic obesity (SO) is a combination of sarcopenia and obesity that leads to adverse outcomes, such as increased mortality. Multiple pathways of SO have been proposed, however, the upstream determinants of SO, such as socioeconomic status (SES), have not been well established.

Methods: This was a secondary analysis of the English Longitudinal Study of Ageing (ELSA). A total of 6,522 participants from the wave 2 dataset (2004-2005) were initially included and followed up at wave 6 (2012-2013). The inclusion criteria were individuals aged 50 to 89 years at entry. The exclusion criteria were the presence of SO at baseline, no data for SO or SES at baseline or SO at follow-up.  SES was defined as a composite score comprising paternal occupation, age of education completion, and household wealth. The participants were divided by SES score using the proposed cutoffs (High: 0–2, Low: 3–6). SO was determined by the ESPEN/EASO criteria. 

Results: There were 3,598 participants (median [interquartile range (IQR)]: 62 [57-69] years, female: 54.8%) with 1,565 (43.5%) and 2,033 participants (56.5%) in the high SES and low SES groups, respectively. During a follow-up, 154 participants became SO (4.3%). Multivariable logistic regression analysis revealed an adverse effect of the SES score (as a continuous variable) on SO (OR: 1.20, 95% CI: 1.08-1.34). There was no effect modification of sex for the SES-SO relationship (P=0.82).

Conclusion: The 8-year incidence of SO was 4.3% among older adults in England. The odds of SO were 1.20 times higher per SES score after adjusting for potential confounders. No evidence was found for the interaction between sex and SES. These findings highlight that individuals with lower SES have a significantly elevated risk of SO, suggesting the need for targeted public health interventions to address this disparity. 

Disclosure of Interest: S. Nishioka Grant / Research Support from: Japan Society of Science Promotion Grant-in-Aid for Early-Career Scientists (No.22K17827), B. Avan: None declared