P614 - PHASE ANGLE MEASURED BY BIA IS EFFECTIVE IN CLASSIFICATION OF MALNUTRITION

P614

PHASE ANGLE MEASURED BY BIA IS EFFECTIVE IN CLASSIFICATION OF MALNUTRITION

M. Tomiska^1,*, H. Hola², S. Tucek¹

¹Internal Medicine Hematology Oncology, ²Medical Nutrition, Faculty Hospital Brno, Brno, Czech Republic

Rationale: To evaluate the relevance of bioelectrical impedance analysis (BIA) data for the diagnosis of protein-energy malnutrition (PEM). Quantification of muscle mass can have the potential for classification of PEM.

Methods: We used the adapted numerical 7-point Subjective Global Assessment (SGA) tool as the gold standard for classification of malnutrition as A (good nutrition status), B (moderate PEM) and C (severe PEM). For comparison, total body Phase Angle (tPA), Skeletal Muscle Mass Index (SMMI) and upper appendicular SMMI (uaSMMI) measured by BIA were analyzed. Correlations between SGA and BIA parameters were calculated and a T-TEST was used to express statistical significance of differences between subgroups of nutrition status. 

Results: The group of 109 cancer pacients at risk of malnutrition was evaluated (mean age 63,8 years, males/females 57/52). Most of the patients were within active treatment (39 pancreatic, 21 gastrointestinal, 30 hematological, and 19 other malignancies).

We found a moderate correlation between fully independent clinical SGA categories and unadjusted tPA directly measured by BIA (R 0,57 for males, R 0,59 for females). Differences of medians tPA between SGA categories in males and females separately were statistically significant between all subgroups (p<0,038 to p<0,00002).

Similar results were found for total body SMMI in males, but the differences between SGA categories were small (SMMI 11,0; 10,3; and 8,8 kg/m² for A, B, and C respectively). Female results of SMMI were even less significant, but uaSMMI seemed to perform better.

Conclusion: Total body unadjusted Phase Angle directly measured by BIA is easily obtainable and effective parameter supporting classicication of nutrition status in cancer patients.

Disclosure of Interest: None declared