P769 - NUTRITION-RELATED FACTORS AFFECT THE PROGNOSIS OF MULTIPLE TRAUMA- A RETROSPECTIVE LONGITUDINAL STUDY

P769

NUTRITION-RELATED FACTORS AFFECT THE PROGNOSIS OF MULTIPLE TRAUMA- A RETROSPECTIVE LONGITUDINAL STUDY

H.-C. Lin^1,2,*

¹Department of Nutrition, Chung Shan Medical University Hospital, ²Department of Nutrition, Chung Shan Medical University, Taichung, Taiwan, Province of China

Rationale: Adequate nutritional support is essential for patients with multiple trauma. The aim of this study was to determine whether mortality could be reduced in this patient population via a nutritional intervention strategy.

Methods: A retrospective longitudinal analysis was performed on the data of all patients with multiple trauma admitted to the ICU of a medical center in central Taiwan from October 2021 to September 2024. The mortality rate of this patient population was analyzed using the Kaplan-Meier method.

Results: In the study population, the mean age of patients was 57.3±24.5 years. Our results showed that in patients admitted to the ward, the HS C.R.P level decreased from 7.3 ± 9.1 mg/dl to 5.6 ± 6.4 mg/dl, the calorie intake increased from 33.2 ± 40.0% to 71.1 ± 28.5% and the protein intake increased from 33.7 ± 63.8% to 82.2 ± 358.2%. In the Cox proportional hazards model, it was found that the adjusted HR for an ISS score of more than 16 was as high as 3.69; conversely, the adjusted HRs for calorie intake reaching 70% of the target energy and protein intake reaching 0.5 g/kg BW were 0.81 and 0.21, respectively. The Kaplan-Meier mortality analysis also obtained consistent results.

Conclusion: The conclusion of this study is that the prognosis of patients with multiple trauma is worse when ISS score ≥ 16, and it is beneficial to consume 70% of target energy goal and 0.5 g protein per kilogram of body weight in the acute phase.

References: 1. Singer P, Blaser AR, Berger MM et al. (2019) ESPEN guideline on clinical nutrition in the intensive care unit. Clin Nutr 38, 48-79.

2. McClave SA, Taylor BE, Martindale RG et al. (2016) Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Adult Critically Ill Patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.). JPEN J Parenter Enteral Nutr 40, 159-211.

Disclosure of Interest: H.-C. Lin Grant / Research Support from: no, Consultant for: no, Speakers Bureau of: no, Shareholder of: no, Paid Instructor at: no, Other: no