P231 - NUTRITIONAL ASSESSMENT FROM A CLINICAL PHARMACY PERSPECTIVE: AN OBSERVATIONAL STUDY

P231

NUTRITIONAL ASSESSMENT FROM A CLINICAL PHARMACY PERSPECTIVE: AN OBSERVATIONAL STUDY

A. Koseoglu^1,*, A. altaii²

¹department of clinical pharmacy, fenerbahçe üniversity ,faculty of pharmacy, ²department of clinical pharmacy, istinye üniversitesi,faculty of pharmacy, istanbul, Türkiye

Rationale: Nutritional deficiency is common in inflammatory bowel disease. In the  guideline , it is recommended that patients be regularly screened for nutritional status at the time of diagnosis and follow-up of IBD . To evaluate the nutritional status, the relationship between fatigue, disability nutritional status and disease activation of patients with IBD by the clinical pharmacist in Istanbul.

Methods:  A descriptive observational study conducted among patients with IBD admited to the IBD center, Istanbul. Disease activation was evaluated using modified Mayo score in UC  and Harvey Bradshaw index in CD . Nutritional status was assessed with S. G. A and laboratory examinations. BIA to determine body composition. BFI  to assess fatigue and IBD-DI-SR for disability. mGPS  score was used as a measure of inflammation.

Results:  30 patients diagnosed with IBD between the ages of 19-70 years old were included in this study. 18 of the patients had CD, 12 had UC. The fat status was low in 81.2% and 4.11% of UC and CD patients, respectively. 13.9% of the UC patients had low muscle mass. For IBD-DI-SR test, the average deficiency score of UC patients was -2.39, and -0.49 for CD patients. Statistically significant correlation between mGPS was found to be associated with clinical activity in both UC and CD (p < 0.001 and p = 0.001, respectively). It was seen that the malnutrition group had a worse prognostic rate than mGPS (p<0.001).

Conclusion:  Fatigue and disability were associated with nutritional status and disease activation. mGPS is associated with both clinical activation and malnutrition.

References: Kuhnen A. Genetic and Environmental Considerations for Inflammatory Bowel Disease.Surg Clin North Am. 2019;99(6):1197-1207. doi:10.1016/j.suc.2019.08.014

Forbes A, Escher J, Hébuterne X, et al. ESPEN guideline: Clinical nutrition in inflammatory bowel disease. Clin Nutr.2017;36(2):321-347. doi:10.1016/j.clnu.2016.12.027

Disclosure of Interest: None declared