PD515 - A CROSS-SECTIONAL EXPLORATION OF DIETARY VITAMIN E AND VITAMIN C INTAKE AMONG VITILIGO PATIENTS

PD515

A CROSS-SECTIONAL EXPLORATION OF DIETARY VITAMIN E AND VITAMIN C INTAKE AMONG VITILIGO PATIENTS

S. Ebrahimpour^1,*, P. Mostafazadeh ¹, A. Nouri Nouri ¹, F. Javadi ², M. Jowshan¹, M. Aghasi¹, A. Haghighi³

¹Department of Clinical Nutrition, Tehran University of Medical Sciences, ²Department of Community Nutrition, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic Of, ³Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, United States

Rationale: Vitiligo, a skin disorder with global prevalence ~1%, involves melanin loss and is linked to hormonal, genetic and dietary factors. This study assesses dietary vitamin C and E intake in vitiligo patients, exploring potential nutritional associations despite unclear mechanistic roles in immune-mediated pathogenesis.

Methods: This hospital-based cross-sectional study analyzed 263 vitiligo patients among Iranian population, assessing dietary intake via a validated 168-item food frequency questionnaire (FFQ). Vitamin C and E consumption levels were calculated using a Nutritionist IV software.

Results: Based on this cross-sectional survey, vitiligo patients showed a mean vitamin E intake of 3.79±1.80 mg/day, which is significantly lower than the RDA value (15 mg/day), indicating deficiency. Conversely, their average vitamin C consumption (130.70 ± 84.00 mg/day) exceeded the RDA (90 mg/day). 

Conclusion: In conclusion vitiligo patients often exceed vitamin C recommendations due to higher intake of fruits/vegetables containing vitamin C, while lower vitamin E intake might be caused from limited consumption of nuts/seeds/oils, economic constraints, and dietary habits of Iranian.

References:         1. Hedayat K, Karbakhsh M, Ghiasi M, Goodarzi A, Fakour Y, Akbari Z, et al. Quality of life in patients with vitiligo: a cross-sectional study based on Vitiligo Quality of Life index (VitiQoL). Health and quality of life outcomes. 2016; 14:1-9.

        2. Sehgal VN, Srivastava G. Vitiligo: compendium of clinico-epidemiological features. Indian journal of dermatology, venereology and leprology. 2007; 73:149.

        3. Hadi Z, Kaur R, Parekh Z, Khanna S, Khalil ABB, Abbasi HQ, et al. Exploring the impact of diet and nutrition on vitiligo: A systematic review of dietary factors and nutritional interventions. Journal of cosmetic dermatology. 2024;23(7):2320-7.

Disclosure of Interest: None declared