PP476
ASSOCIATION OF DEHYDRATION WITH GERIATRIC CLINICAL INDICATORS: A CROSS-SECTIONAL ANALYSIS IN OLDER ADULTS
E. Chouseın1,*, Ö. Özgün2, M. Eşme2, C. Balcı2, B. B. Doğu2, M. Cankurtaran2, M. G. Halil2
1Division of Internal Medicine, 2Division of Geriatrics, Hacettepe University, Ankara, Türkiye
Rationale: In older adults, physiological changes, comorbidities, polypharmacy, and geriatric syndromes increase the risk of dehydration. This study aimed to evaluate the relationship between dehydration and geriatric syndromes, and to identify associated risk factors, using calculated serum osmolarity in geriatric outpatient clinic patients.
Methods: This retrospective cross-sectional study included 2555 patients aged ≥65 years who were admitted to the Geriatrics Outpatient Clinic. Dehydration was defined as a calculated serum osmolarity of ≥300 mOsm/kg, based on a formula validated by Hooper et al.(1). Patients underwent comprehensive geriatric assessment. Independent factors associated with dehydration were evaluated using multivariable logistic regression analysis.
Results: A total of 2555 patients (mean age: 74.4 ± 6.3 years; 63.9% female) were analyzed, and the prevalence of dehydration was 29.5% (n=754). Patients with dehydration had higher frailty scores, greater comorbidity burden, more frequent polypharmacy, and lower physical performance, nutritional, and cognitive scores (all p<0.001). In multivariate analysis, older age (OR: 1.02; 95% CI: 1.005–1.040), type 2 diabetes mellitus (OR: 1.65; 95% CI: 1.35–2.02), chronic kidney disease (OR: 2.82; 95% CI: 2.30–3.47), SGLT-2 inhibitor use (OR: 1.80; 95% CI: 1.31–2.48), Clinical Frailty Scale score (OR: 1.11; 95% CI: 1.01–1.21), history of falls (OR: 1.22; 95% CI: 1.00–1.49), and urinary incontinence (OR: 1.22; 95% CI: 1.00–1.50) were independently associated with dehydration.
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Conclusion: Dehydration, defined by calculated serum osmolarity is a common and multidimensional clinical condition in older adults, closely associated with functional impairment and geriatric syndromes, particularly in frail patients.
References: 1. Hooper L, et al. Diagnostic accuracy of calculated serum osmolarity to predict dehydration in older people. BMJ Open. 2015;5:e008846.
Disclosure of Interest: None declared