PD582 - LONGITUDINAL CHANGES IN BODY COMPOSITION, RESTING METABOLIC RATE, AND BONE HEALTH FOLLOWING SLEEVE GASTRECTOMY

PD582

LONGITUDINAL CHANGES IN BODY COMPOSITION, RESTING METABOLIC RATE, AND BONE HEALTH FOLLOWING SLEEVE GASTRECTOMY

A. Alzaben^1,*, S. A. Alothman², A. A. Al-Masud ³, D. F. Alshamri⁴, S. S. Alshlwi⁵

¹Department of Health Sciences, College of Health and Rehabilitation Sciences, ²Lifestyle and Health Research, Health Sciences Research Center, ³Tissue Banking Section, Research Department, Health Science Research Center, Princess Nourah Bint Abdulrahman University, ⁴Department of Nutrition, ⁵Department of Surgery, King Abdullah Bin Abdulaziz University Hospital, Riyadh, Saudi Arabia

Rationale: While the effects of sleeve gastrectomy (SG) on weight loss and metabolic outcomes are well established, evidence on its longer-term impact on body composition, resting metabolic rate (RMR), and bone health remains limited. The objective of the study was to assess changes in body composition, RMR, cardiometabolic profile, and bone health over one year following SG.

Methods: A one-year prospective study recruited patients prior to SG and followed at three postoperative time points: 3, 6, and 12 months. Data collected included anthropometric measures, body composition, and bone health using Dual-Energy X-ray Absorptiometry; RMR using indirect calorimetry; and blood draws. All participants received follow-up care from a registered dietitian for nutrition and lifestyle recommendations. 

Results: A total of 63 patients undergoing SG were included (68% females and 32% males), with a mean age of 35 ± 12 years old. Cardiometabolic profile including fasting blood glucose, triglycerides, liver function and C-reactive protein were significantly lower at 1-year post-SG compared to pre-SG (P < 0.05). The percentage of fat mass declined from 51.6 ± 5.5 pre-SG to 35.8 ± 8.7 1-year post SG whereas The percentage of fat-free mass percentage rose from 48.4 ± 5.5 pre-SG to 64.02 ± 8.74 1-year post SG (P < 0.001).No statistically significant changes were observed in total body T-scores for bone health (0.860 ± 1.00 at baseline vs. 0.802 ± 0.868 at 3 months vs. 0.735 ± 0.877 at 6 months vs. 0.635 ± 1.04 at 12 months; P > 0.05).  RMR was reduced from 2258 ± 675 kcal/d pre-SG to 1769 ± 787 kcal/d at 1 year post SG (P = 0.02).  

Conclusion: Although SG effectively reduces fat mass, RMR and improves markers of cardiometabolic dysfunction, bone health may be a concern in this population. Post-bariatric care programs should adopt a multidisciplinary approach to address both metabolic and skeletal outcomes.

Disclosure of Interest: None declared