PD950 - ASSESSMENT OF THE IMPLEMENTATION OF THE “EUROPEAN RECOMMENDATIONS ON PARENTERAL NUTRITION FOR CHILDREN” IN PEDIATRIC ONCOLOGY PATIENTS

PD950

ASSESSMENT OF THE IMPLEMENTATION OF THE “EUROPEAN RECOMMENDATIONS ON PARENTERAL NUTRITION FOR CHILDREN” IN PEDIATRIC ONCOLOGY PATIENTS

D. Bartkowiak^1,*, M. Jakubczyk², A. Klarkowska³, M. Richert-Przygońska⁴, S. Kołtan¹, B. Jakubczyk⁵

¹Department of Pediatrics, Hematology and Oncology, CM UMK– Student Scientific Association, ²Department of Anaesthesiology and Intensive Care CM.UMK, Nicolaus Copernicus University in Toruń, Collegium Medicum in Bydgoszcz, Bydgoszcz, Poland, ³Hospital Pharmacy, University Hospital No. 1 named after Dr. Antoni Jurasz in Bydgoszcz, ⁴Department of Pediatrics, Hematology and Oncology, CM UMK, ⁵Departments of General Surgery, Liver Surgery and Transplant Surgery– Student Scientific Association, Bydgoszcz, Poland

Rationale: The treatment of childhood cancers predominantly relies on intensive chemotherapy,which,aside from its intended therapeutic effects, is associated with numerous complications (such as gastrointestinal mucositis,diarrhea,vomiting, and toxic injury to the kidneys,liver, and pancreas). Consequently,these patients require comprehensive, multidisciplinary management during therapy, including specialized dietary and nutritional support.This study aimed to evaluate the composition of parenteral nutrition mixtures administered to pediatric oncology patients in comparison with the 2018 European Recommendations on Pediatric Parenteral Nutrition (ESPGHAN/ESPEN).

Methods: A retrospective analysis was conducted on 8,277 parenteral nutrition prescriptions, each administered for more than 16hours (constituting complete nutrition), prescribed to290patients treated at the Department of Pediatrics, Hematology, and Oncology at University Hospital No.1in Bydgoszcz between May 2019 and September 2025. Nutritional regimens were tailored to each patient's clinical status and laboratory results, based on the 2018 ESPGHAN/ESPEN guidelines and modified as needed. The prescriptions were reviewed across 5age groups: infants up to 1year, children aged 1-3years, 4-7years, 8-12years, and adolescents aged 13-18years.

Results: The results of the study are summarized in the table below.

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Conclusion: The observed discrepancies between recommended and actual nutritional practices suggest reduced tolerance to certain nutrients - most notably lipids - and indicate significant electrolyte losses in pediatric oncology patients. The wide variability in nutrient intake underscores the necessity for ongoing, individualized adjustments to parenteral nutrition regimens.

Disclosure of Interest: None declared