PD1058 - THE EFFECTS OF PERIOPERATIVE NUTRITIONAL SUPPORT ON MORTALITY, MORBIDITY, AND SURVIVAL IN PATIENTS UNDERWENT SURGICAL RESECTION FOR PRIMARY LUNG CANCER TREATMENT.

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PD1058

THE EFFECTS OF PERIOPERATIVE NUTRITIONAL SUPPORT ON MORTALITY, MORBIDITY, AND SURVIVAL IN PATIENTS UNDERWENT SURGICAL RESECTION FOR PRIMARY LUNG CANCER TREATMENT.

C. E. Kalafat1,*, S. Kalafat2, Z. K. Ozerson3, C. B. Sezen4, C. I. Kocaturk1

1Thoracic Surgery, Medicana Zincirlikuyu Hospital, 2Department of Nutrition and Dietetics, Yedikule Chest Diseases and Chest Surgery Hospital, 3Department of Nutrition and Dietetics, Halic University, 4Department of Thoracic Surgery, Universiy of Health Sciences Yedikule Chest Diseases and Chest Surgery Hospital, Istanbul, Türkiye

 

Rationale: Aim of the study is evaluate morbidity, mortality, and 5-year survival rates for patients undergoing primary non-small cell lung cancer surgery. Patients were monitored or provided nutritional support based on  nutritional assessments.

Methods: Study was carried out retrospectively on 181 patients with from prospectively collected data. Descriptive statistics, Chi-square, Mann-Whitney-u, Kaplan Meier survival and cox  regression analysis were used. 

Results: The rate of major complications was 18.8%. Pneumonectomy, chest wall resections and not receiving nutritional support were increased major complication rate by 4,6; 7,8 and 10,1 times respectively. Post operative 1 month, 12 patients withdrew from receiving nutrirional support whom 11 were stage 1 lung cancer.  Overall survival was 72,5 months with 5 year survival rate was 60,2%. While pathological subtype, minimally invasive surgical method, NRS 2002 score, and preoperative or postoperative nutritional support status did not affect survival; male gender (53.7%), pneumonectomy (37.1%), development of major complications (41.2%), and up stage (69.1%, 54.9%, 42.4%, ascending order respectively) significantly decreased 5 year survival rate. Cox analysis revealed that male gender, major complications, pneumonectomy, and N2 disease reduced survival by 8.7, 7.1, 5.4, and 5.1 times, respectively.

Conclusion: Nutritional support descreased the incidence of  major complications significantly, while hospitalization time was shortened, and albumin loss was less in the postoperative first three months. Although it has not been identified as a single factor affecting survival,  patients that planning extended lung resections (pneumonectomy or chest wall resections) should be given nutritional support  to avoid major complications and poor survival rates.

Disclosure of Interest: None declared