P793 - THE IMPACT OF VITAMINS ON ENDOMETRIOSIS: A SYSTEMATIC REVIEW

P793

THE IMPACT OF VITAMINS ON ENDOMETRIOSIS: A SYSTEMATIC REVIEW

A. Spiljak^1,*, A. Gazibara²

¹Institute for Healthcare of Transportation Employees Sarajevo, ²University of Sarajevo, Professor Zdravko Grebo Center for Interdisciplinary Studies (CIS), Sarajevo, Bosnia and Herzegovina

Rationale: The scientific question of this study is to assess the impact of vitamins on the management of endometriosis symptoms, focusing on their potential role in reducing inflammation, oxidative stress and hormonal imbalances. Clinically, this research is important as it may provide evidence for the use of vitamins as a complementary therapeutic option, improving the quality of life for women affected by endometriosis.

Methods: For this systematic review, a comprehensive literature search was conducted using PubMed to identify studies published in English that examine the impact of vitamins on the intensity of endometriosis symptoms.

Results: A total of 20 studies from PubMed investigated the impact of vitamins on endometriosis symptoms, including randomized controlled trials, observational studies, and clinical trials. The studies focused on vitamin D, E, C, B6, and folate, highlighting their anti-inflammatory and antioxidant properties. Low vitamin D levels are linked to more severe symptoms, and supplementation may reduce pain. Vitamin E may alleviate pelvic pain by reducing oxidative stress, while vitamin C helps reduce inflammation and improve immune function. Vitamin B6 may help with premenstrual symptoms, and folate may reduce symptom severity by supporting immune health. However, further research is needed for definitive conclusions.

Conclusion: The studies included in this review highlight the potential benefits of antioxidant vitamins in managing endometriosis. Supplementing with these vitamins was found to significantly reduce the severity of dysmenorrhea, alleviate dyspareunia and pelvic pain, and improve the overall quality of life for patients. As a result, antioxidant vitamin therapy could be considered a viable alternative treatment, either alone or in combination with other therapies, for alleviating endometriosis-related pain.

Disclosure of Interest: None declared