Sep 5, 2026
2:00 PM12:00 PM
ePoster display
PD134
IMPACT OF DYNAPENIA ON PULMONARY FUNCTION IN POST-COVID PATIENTS
L. Ramírez-Morales1,2,*, A. Orea-Tejeda2, D. González-Islas2, J. García-Hernández2, D. Bonilla-Cuatepotzo2, K. García-Díaz2, V. Maldonado-Vargas2, G. Cruz-Gijón2, G. Rentería-Serralde 2, S. Alday-Ramirez 2, R. Sánchez-Santillán 2, B. Valderrábano-Salas2, G. Benítez-Moya 2, J. Ruan-Díaz 2, E. Vargas-Corona 2, J. De la Borda-Paredes 2
1Licenciatura en Fisioterapia, Universidad Metropolitana de Tlaxcala, Tlaxcala, 2Unidad Clínica de Investigación Cardiopulmonar y Metabólica. Servicio de Cardiología, Instituto Nacional de Enfermedades Respiratorias, Ismael Cosío Villegas, Ciudad de México , Mexico
Rationale: Post-COVID syndrome is defined as the persistence of symptoms following COVID-19 infection1. The mechanisms include inflammation, oxidative stress, and endothelial injury2. Dynapenia is defined as low muscle strength and is associated with the worst clinical results1. However, the impact of dynapenia on pulmonary function in post-COVID patients is unknown.
Methods: A cross-sectional study that included patients with post-COVID-19 syndrome aged 18 years or older; subjects diagnosed with HIV were excluded. Functional capacity was assessed using the 6-minute walk test.
Results: Dynapenia subjects were older (58.57 ± 13.28 vs. 49.34 ± 12.33), had a higher prevalence of hypertension (43.91% vs. 31.33%) diabetes (43.59% vs. 27.82%), and sarcopenia (54.46% vs. 34.21%), as well as lower FEV1 (2.44 ± 0.70 vs. 2.98 ± 0.70), expiratory peak flow (7.69 ± 2.70 vs. 9.38 ± 2.48), diaphragm strength (84.66 ± 26. 76 vs 103±25.63), intercostal muscle strength (105.99±34.86 vs 127.63±35.69), and lower walking distance (419.20±111.60 vs 496.17±97.11) compared to subjects without dynapenia.
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Conclusion: Dynapenia was associated with worse pulmonary function in post-COVID-19 subjects
References: Orea-Tejeda A, et al. Dynapenia and sarcopenia in post-COVID-19 syndrome hospitalized patients are associated with severe reduction in pulmonary function. J Clin Med. 2023;12(20):6466. Available from: http://dx.doi.org/10.3390/jcm12206466
Negrut N, et al. The multisystem impact of Long COVID: A comprehensive review. Diagnostics (Basel). 2024;14(3):244. Available from: http://dx.doi.org/10.3390/diagnostics14030244
Disclosure of Interest: None declared